Cannabis and cannabinoids have been suggested as a potential therapy for liver disease. The principal causes for chronic liver disease are viral hepatitis, alcoholic liver disease, and non-alcoholic fatty liver disease (NAFLD). Obesity is an increasing common cause for NAFLD due to excessive accumulation of triglycerides in liver, which leads to inflammation and variable degrees of liver fibrosis overtime, eventually causing steatohepatitis.
One recent animal study showed that non-psychoactive THCA, the most abundant natural cannabinoid and precursor of THC in cannabis plants, significantly reduced body weight, improved glucose tolerance, and drastically attenuated liver fibrosis and inflammation in obesity induced NAFLD.
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